Why is Artemisa annua (whole plant extract) effective?

Anamed uses a rich whole extract, not simply “poorified” artemisinin to treat malaria, because it contains more then 50 chemicals with…

Antiplasmodial Activity:
Chrysosplenetin, Chrysosplenol-D, Oleanolic-Acid, Quercetin

Antimalarial Activity:
Artemetin, Artemisinin, Ascaridole, Casticin, Chrysosplenetin, Chrysosplenol-D, Cirsilineol, Eupatorin, Oleanolic-Acid, Quercetin

Analgesic Activity (against fever):
Alpha-amyrin, Alpha-bisabolol, Ascaridole, Beta-amarin, Borneol, Camphor, Coumarin, Menthol, Myrcene, P-Cymene, Quercetin, Scoparone, Scopoletin, Thymol

Anticolitic Activity (against colic):
Quercetin

Antidiarrheic Activity:
Camphor

Antiemetic Activity (against vomiting):
Camphor

Antipyretic Activity (against fever):
Alpha-bisabolol, Beta-sitosterol, Borneol, Menthol

Antispasmodic Activity:
1,8-Cineole, Alpha-bisabolol, Alpha-pinene, Alpha-terpinene, Apigenin, Beta-pinene, Borneol, Bornyl-acetate, Camphor, Carvacrol, Cirsilineol, Geraniol, Isorhamnetin, Kaempferol, Limonene, Linalool, Luteolin, Menthol, Myrcene, Patuletin, Quercetin, Scoparone, Scopoletin, Terpinen-4-ol, Thymol

Diuretic Activity (for cleansing the body):
Apigenin,Friedelin, Isoquercitrin, Kaempferol, Luteolin, Oleanolic-Acid, Terpinen-4-ol

Immunostimulant Activity:
Astragalin, Coumarin, Eupatorin

Mosquitocide Activity (kills mosquitoes):
Beta-amyrin

Sedative Activity:
1,8-Cineole, Alpha-pinene, Alpha-terpineol, Apigenin, Ascaridole, Borneol, Bornyl-acetate, Carvone, Coumarin, Cuminaldehyde, Geraniol, Isoeugenol, Limonene, Linalool, Oleanolic-Acid, P-cymene, Stigmasterol, Thymol

Antithrombotic Activity (avoids blod clotting as in cerebral malaria):
Quercetin

This is the complete list of artemisia chemicals activities:
Activities
The number in () indicates how many separate chemicals this species has for that activity, for example, Analgesic (3) indicates this species has three separate chemicals that have Analgesic activity. Select the activity to see the chemicals.
(-)-Chronotropic (3)
(-)-Inotropic (3)
11B-HSD-Inhibitor (3)
5-Lipoxygenase-Inhibitor (2)
ACE-Inhibitor (6)
AChE-Inhibitor (1)
ATPase-Inhibitor (1)
Abortifacient (1)
Acaricide (7)
Aedifuge (1)
Aldehyde-Oxidase-Inhibitor (1)
Aldose-Reductase-Inhibitor (20)
Allelochemic (7)
Allelopathic (5)
Allergenic (14)
Analgesic (15)
Ancylostomicide (2)
Androgenic (2)
Anesthetic (8)
Angiogenic (1)
Ankylostomacide (1)
Anorexic (1)
Anthelmintic (6)
AntiADD (1)
AntiCrohn’s (1)
AntiGTF (1)
AntiHIV (5)
AntiPGE2 (1)
AntiPMS (1)
AntiTGF-beta (1)
AntiTNF (1)
Antiacetylcholine (1)
Antiacetylcholinesterase (9)
Antiacne (6)
Antiadenomic (2)
Antiadrenergic (1)
Antiaflatoxin (5)
Antiaggregant (7)
Antiaging (2)
Antiallergic (9)
Antialzheimeran (1)
Antialzheimeran? (3)
Antianaphylactic (2)
Antiandrogenic (2)
Antiangiogenic (3)
Antiarrhythmic (3)
Antiarthritic (3)
Antiasthmatic (5)
Antiatherogenic (2)
Antiatherosclerotic (4)
Antibacillary (1)
Antibacillus (1)
Antibacterial (31)
Antibronchitic (4)
Antibronchoconstrictor (1)
Antibrucellosic (1)
Antiburn (1)
Anticancer (5)
Anticancer (Breast) (1)
Anticancer (Cervix) (2)
Anticancer (Kidney) (1)
Anticancer (Lung) (2)
Anticancer (Pancreas) (1)
Anticancer (Prostate) (1)
Anticarcinogenic (1)
Anticarcinomic (3)
Anticarcinomic (Breast) (1)
Anticariogenic (8)
Anticataract (2)
Anticatarrh (1)
Anticholinergic (2)
Anticholinesterase (2)
Anticholinesterase? (1)
Anticolic (1)
Anticolitic (1)
Anticomplement (1)
Anticomplementary (5)
Anticonvulsant (3)
Anticystitic (1)
Antidandruff (1)
Antidepressant (1)
Antidermatic (1)
Antidermatitic (2)
Antidiabetic (1)
Antidiarrheic (1)
Antidiuretic (2)
Antidysenteric (1)
Antiedemic (10)
Antielastase (2)
Antiemetic (1)
Antiencephalitic (1)
Antiescherichic (3)
Antiesherichic (1)
Antiesophagitic (1)
Antiestrogenic (4)
Antifatigue (1)
Antifeedant (12)
Antifertility (3)
Antifibrosarcomic (1)
Antifibrositic (1)
Antiflatulent (1)
Antiflu (5)
Antigastric (1)
Antigingivitic (3)
Antigliomic (1)
Antiglutamaergic (1)
Antigonadotrophic (1)
Antigonadotropic (1)
Antihalitosic (3)
Antihelicobacter (1)
Antihepatotoxic (5)
Antiherpetic (6)
Antihistaminic (7)
Antihydrophobic (1)
Antihyperlipidemic (1)
Antihyperlipoproteinaemic (1)
Antihypertensive (1)
Antihyperthyroid (1)
Antiimplantation (2)
Antiinflammatory (33)
Antiischemic (2)
Antilaryngitic (1)
Antileishmanic (1)
Antilepric (1)
Antileukemic (8)
Antileukotriene (3)
Antileukotrienogenic (1)
Antilipoperoxidant (1)
Antilisteria (1)
Antilithic (1)
Antilithic? (1)
Antilymphedemic (1)
Antilymphocytic (1)
Antilymphomic (4)
Antimalarial (15)
Antimange (1)
Antimelanomic (7)
Antimetastatic (3)
Antimetastatic (Stomach) (1)
Antimite (2)
Antimitotic (1)
Antimononuccleotic (1)
Antimutagenic (12)
Antimycoplasmotic (1)
Antimyocarditic (1)
Antinephritic (1)
Antineuralgic (2)
Antineuritic (1)
Antinitrosaminic (3)
Antinociceptive (9)
Antiobesity (1)
Antiodontalgic (1)
Antiophidic (2)
Antiotitic (1)
Antioxidant (20)
Antioxidant (LDL) (2)
Antipancreatitic (1)
Antiparkinsonian (1)
Antipeptic (1)
Antiperiodontal (1)
Antiperiodontic (4)
Antiperistaltic (2)
Antipermeability (1)
Antiperoxidant (2)
Antipharyngitic (2)
Antiplaque (7)
Antiplasmodial (9)
Antipneumonic (1)
Antipodriac (1)
Antipolio (3)
Antiprogestational (1)
Antiproliferant (7)
Antiproliferative (1)
Antiprostaglandin (3)
Antiprostanoid (1)
Antiprostatadenomic (1)
Antiprostatitic (2)
Antipruritic (2)
Antipsittacotic (1)
Antipsoriac (2)
Antipyretic (4)
Antiradicular (7)
Antiretinopathic (1)
Antirheumatalgic (1)
Antirheumatic (3)
Antirhinitic (1)
Antirhinoviral (4)
Antisalmonella (4)
Antisarcomic (1)
Antiseptic (20)
Antiserotonin (1)
Antishock (1)
Antisinusitic (2)
Antispasmodic (25)
Antistaphylococcic (7)
Antistreptococcic (5)
Antistress (1)
Antitartar (1)
Antithiamin (1)
Antithrombic (1)
Antithyroid (1)
Antitoxoplasmotic (1)
Antitrichinosic (1)
Antitrypanosomic (1)
Antitubercular (1)
Antituberculic (1)
Antitumor (19)
Antitumor (Bladder) (1)
Antitumor (Breast) (5)
Antitumor (Cervix) (2)
Antitumor (Colon) (4)
Antitumor (GI) (1)
Antitumor (Kidney) (3)
Antitumor (Lung) (5)
Antitumor (Ovary) (2)
Antitumor (Pancreas) (4)
Antitumor (Prostate) (2)
Antitumor (Skin) (3)
Antitumor (Stomach) (2)
Antitumor (Thyroid) (1)
Antitumor (brain) (1)
Antitumor-Promoter (4)
Antitussive (5)
Antiulcer (9)
Antivaginitic (1)
Antiviral (23)
Antivulvitic (1)
Antiyeast (1)
Anxiolytic (1)
Aphidifuge (1)
Apoptotic (8)
Aromatase-Inhibitor (4)
Artemicide (2)
Ascaricide (1)
Ataxigenic (1)
Bacteriostatic (1)
Bacteristat (3)
Barbituate-Synergist (1)
Beta-Blocker (1)
Beta-Glucuronidase-Inhibitor (3)
Bradycardiac (1)
Bradycardic (1)
Bronchomucolytic (1)
Bronchomucotropic (1)
Bronchoprotectant (1)
Bronchorelaxant (3)
Bronchorrheic (1)
Bruchiphobe (1)
CNS-Depressant (6)
CNS-Stimulant (7)
CNS-Toxic (1)
COMT-Inhibitor (1)
COX-1-Inhibitor (2)
COX-2-Inhibitor (5)
Calcium-Antagonist (4)
Calcium-Antagonist? (1)
Calmodulin-Antagonist (1)
Cancer-Preventive (23)
Candidicide (11)
Candidistat (4)
Capillarigenic (1)
Capillariprotective (1)
Carcinogenic (5)
Cardiac (1)
Cardiodepressant (1)
Cardioprotective (1)
Cardiotonic (2)
Carminative (7)
Caspase-8-Inducer (1)
Catabolic (1)
Chemopreventive (4)
Cholagogue (3)
Choleretic (9)
Cholesterolytic (1)
Cicatrizant (2)
Ciliotoxic (1)
Coleopterifuge (1)
Coleoptophile (1)
Congestant (1)
Convulsant (4)
Copper-Chelator (2)
Cosmetic (2)
Counterirritant (4)
Culicide (2)
Cyclooxygenase-Inhibitor (6)
Cytochrome-P450-1A1-Inhibitor (1)
Cytochrome-P450-1A2-Inhibitor (1)
Cytochrome-P450-Inducer (2)
Cytotoxic (12)
DME-Inhibitor (1)
DNA-Protective (1)
Decongestant (2)
Decongestant? (1)
Degranulant (1)
Deiodinase-Inhibitor (3)
Deliriant (1)
Dentifrice (2)
Deodorant (1)
Dermatitigenic (2)
Detoxicant (1)
Diaphoretic (2)
Diaphoretic? (2)
Differentiator (3)
Diuretic (7)
Dye (1)
Ecbolic (1)
Edemagenic (1)
Elastase-Inhibitor (1)
Embryotoxic (1)
Emetic (4)
Emmenagogue (1)
Enterocontractant (1)
Enterorelaxant (3)
Enterotoxic (1)
Epileptigenic (2)
Estrogenic (7)
Expectorant (12)
FLavor (20)
Febrifuge (1)
Fungicide (19)
Fungiphilic (1)
Fungistat (3)
GABA-nergic (1)
GST-Inducer (1)
Gastroirritant (1)
Gastroprotective (3)
Gastrosedative (1)
Glucosyl-Transferase-Inhibitor (1)
Gonadotrophic (1)
Gram(+)icide (2)
Gram(-)icide (2)
HIF-1alpha-Inhibitor (1)
HIV-RT-Inhibitor (2)
Hemorrhagic (1)
Hemostat (1)
Hepatomagenic (1)
Hepatoprotective (12)
Hepatotonic (1)
Hepatotoxic (1)
Herbicide (12)
Histaminic (1)
Hyaluronidase-Inhibitor (2)
Hypnotic (2)
Hypocholesterolemic (5)
Hypocholesterolemic? (1)
Hypoglycemic (4)
Hypolipemic (1)
Hypolipidemic (2)
Hypotensive (8)
Hypothermic (2)
ICAM-1-Inhibitor (3)
IKK-Inhibitor (2)
Immunomodulator (3)
Immunostimulant (3)
Immunosuppressant (1)
Inflammatory (1)
Inhalant (1)
Inotropic (3)
Insect-Repellent (2)
Insecticide (10)
Insectifuge (21)
Insectiphile (4)
Insulinogenic (1)
Interleukin-6-Inhibitor (3)
Iodothyronine-Deiodinase-Inhibitor (2)
Irritant (15)
JNK-Inhibitor (1)
Juvabional (2)
Larvicide (4)
Larvistat (2)
Laxative (1)
Leucocytogenic (1)
Lipolytic (1)
Lipoxygenase-Inhibitor (4)
Lymphocytogenic (1)
Lymphokinetic (1)
MAO-A-Inhibitor (1)
MAO-Inhibitor (4)
MAPK-Inhibitor (2)
MDR-Inhibitor (1)
MMP-9-Inhibitor (2)
Mast-Cell-Stabilizer (1)
Metal-Chelator (Copper) (1)
Metalloproteinase-Inhibitor (2)
Molluscicide (1)
Mosquitocide (1)
Mosquitofuge (2)
Motor-Depressant (4)
Motor-Stimulant (1)
Musculotropic (3)
Mutagenic (4)
Mycobactericide (1)
Myorelaxant (11)
NADH-Oxidase-Inhibitor (2)
NEP-Inhibitor (2)
NF-kB-Inhibitor (4)
NO-Genic (1)
NO-Inhibitor (3)
NO-Synthase-Inhibitor (2)
Narcotic (1)
Natriuretic (1)
Nematicide (13)
Neurodepressant (1)
Neuropathogenic (1)
Neuroprotective (2)
Neurotoxic (3)
Nociceptive (1)
Nodulation-Signal (1)
Occuloirritant (1)
Ornithine-Decarboxylase-Inhibitor (3)
Ovicide (1)
Ovulant (1)
Ozone-Scavenger (1)
P21-Inducer (1)
P450-2B1-Inhibitor (4)
P450-Inducer (4)
P450-Inhibitor (1)
PAF-Inhibitor (1)
PGE2-Inhibitor (1)
PKC-Inhibitor (1)
PTK-Inhibitor (3)
Parasiticide (6)
Pediculicide (1)
Perfume (1)
Perfumery (24)
Peristaltic (1)
Pesticide (58)
Phagocytotic (2)
Pheromone (1)
Phospholipase-Inhibitor (1)
Photosensitizer (1)
Phytoalexin (1)
Phytohormonal (1)
Piscicide (2)
Plasmodicide (9)
Polyamine-Synthesis-Inhibitor (1)
Progestational (1)
Proliferant (2)
Prooxidant (1)
Prostaglandin-Inhibitor (1)
Prostaglandin-Synthesis-Inhibitor (2)
Prostaglandin-Synthetase-Inhibitor (1)
Protein-Kinase-C-Inhibitor (3)
Protisticide (5)
Quinone-Reductase-Inducer (5)
Radioprotective (1)
Refrigerant (1)
Renoirritant (1)
Respirainhibitor (1)
Respirastimulant (1)
Respirodepressant (1)
Rodenticide (1)
Rubefacient (3)
Schizonticide (1)
Secretogogue (1)
Sedative (18)
Spasmogenic (5)
Spermicide (2)
Sprout-Inhibitor (1)
Stimulant (2)
Succinoxidase-Inhibitor (1)
Sunscreen (1)
Surfactant (1)
TNF-alpha-Inhibitor (5)
Teratogenic (1)
Teratologic (2)
Termiticide (2)
Termitifuge (1)
Testosterone-Hydroxylase-Inducer (1)
Testosterone-Inducer (1)
Topoisomerase-I-Inhibitor (4)
Topoisomerase-II-Inhibitor (4)
Toxic (1)
Tracheorelaxant (2)
Tranquilizer (3)
Transdermal (8)
Trichomonicide (7)
Trichomonistat (1)
Trypanocide (1)
Trypsin-Enhancer (1)
Tumor-Promoter (1)
Tumorigenic (1)
Tyrosinase-Inhibitor (3)
Tyrosine-Kinase-Inhibitor (1)
Ubiquiot (1)
Ulcerogenic (2)
Urinary-Antiseptic (1)
Uterosedative (1)
Uterotonic (1)
Uterotrophic (2)
VEGF-Inhibitor (3)
Varroacide (1)
Vasodilator (6)
Vasopressor (1)
Vermicide (2)
Vermifuge (2)
Verrucolytic (1)
Vibriocide (2)
Vulnerary (3)
Xanthine-Oxidase-Inhibitor (3)
cAMP-Phosphodiesterase-Inhibitor (2)
iNOS-Inhibitor (4)

Taken from Dr. Duke’s Phytochemical and Ethnobotanical Databases. 23 March 2014:
http://sun.ars-grin.gov:8080/npgspub/xsql/duke/pl_act.xsql?taxon=120

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